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Gliotoxicity of the cyanotoxin, β-methyl-amino-(L)-alanine (BMAA)

The amino acid variant β-methyl-amino-(L)-alanine (BMAA) has long been associated with the increased incidence and progression of the amyotrophic lateral sclerosis/Parkinsonism dementia complex (ALS/PDC). Previous studies have indicated that BMAA damages neurons via excitotoxic mechanisms. We have c...

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Detalles Bibliográficos
Autores principales: Chiu, Alexander S., Gehringer, Michelle M., Braidy, Nady, Guillemin, Gilles J., Welch, Jeffrey H., Neilan, Brett A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601369/
https://www.ncbi.nlm.nih.gov/pubmed/23508043
http://dx.doi.org/10.1038/srep01482