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A High-Throughput, Flow Cytometry-Based Method to Quantify DNA-End Resection in Mammalian Cells

Replication protein A (RPA) is an essential trimeric protein complex that binds to single-stranded DNA (ssDNA) in eukaryotic cells and is involved in various aspects of cellular DNA metabolism, including replication and repair. Although RPA is ubiquitously expressed throughout the cell cycle, it loc...

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Detalles Bibliográficos
Autores principales: Forment, Josep V, Walker, Rachael V, Jackson, Stephen P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601416/
https://www.ncbi.nlm.nih.gov/pubmed/22893507
http://dx.doi.org/10.1002/cyto.a.22155