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Evaluating the use of Apo-neocarzinostatin as a cell penetrating protein

Protein–ligand complex neocarzinostatin (NCS) is a small, thermostable protein-ligand complex that is able to deliver its ligand cargo into live mammalian cells where it induces DNA damage. Apo-NCS is able to functionally display complementarity determining regions loops, and has been hypothesised t...

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Detalles Bibliográficos
Autores principales: Moody, Paul, Burlina, Fabienne, Martin, Stephen R., Morgan, Rachel E., Offer, John, Smith, Mark E.B., Molloy, Justin E., Caddick, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601848/
https://www.ncbi.nlm.nih.gov/pubmed/23322746
http://dx.doi.org/10.1093/protein/gzs104