Protein Kinase Activity of Phosphoinositide 3-Kinase Regulates Cytokine-Dependent Cell Survival

The dual specificity protein/lipid kinase, phosphoinositide 3-kinase (PI3K), promotes growth factor-mediated cell survival and is frequently deregulated in cancer. However, in contrast to canonical lipid-kinase functions, the role of PI3K protein kinase activity in regulating cell survival is unknow...

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Detalles Bibliográficos
Autores principales: Thomas, Daniel, Powell, Jason A., Green, Benjamin D., Barry, Emma F., Ma, Yuefang, Woodcock, Joanna, Fitter, Stephen, Zannettino, Andrew C. W., Pitson, Stuart M., Hughes, Timothy P., Lopez, Angel F., Shepherd, Peter R., Wei, Andrew H., Ekert, Paul G., Guthridge, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601961/
https://www.ncbi.nlm.nih.gov/pubmed/23526884
http://dx.doi.org/10.1371/journal.pbio.1001515

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601961/
https://www.ncbi.nlm.nih.gov/pubmed/23526884
http://dx.doi.org/10.1371/journal.pbio.1001515

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