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Nedd8 processing enzymes in Schizosaccharomyces pombe

BACKGROUND: Conjugation of the ubiquitin-like modifier Nedd8 to cullins is critical for the function of SCF-type ubiquitin ligases and thus facilitates ubiquitin conjugation and ultimately degradation of SCF substrates, including several cell cycle regulators. Like ubiquitin, Nedd8 is produced as a...

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Detalles Bibliográficos
Autores principales: O’Donoghue, Jean E, Bech-Otschir, Dawadschargal, Larsen, Ida B, Wallace, Mairi, Hartmann-Petersen, Rasmus, Gordon, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602023/
https://www.ncbi.nlm.nih.gov/pubmed/23496905
http://dx.doi.org/10.1186/1471-2091-14-8