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TRPV1, but not TRPA1, in primary sensory neurons contributes to cutaneous incision-mediated hypersensitivity

BACKGROUND: Mechanisms underlying postoperative pain remain poorly understood. In rodents, skin-only incisions induce mechanical and heat hypersensitivity similar to levels observed with skin plus deep incisions. Therefore, cutaneous injury might drive the majority of postoperative pain. TRPA1 and T...

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Detalles Bibliográficos
Autores principales: Barabas, Marie E, Stucky, Cheryl L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602024/
https://www.ncbi.nlm.nih.gov/pubmed/23497345
http://dx.doi.org/10.1186/1744-8069-9-9