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Th17 cytokines induce pro-fibrotic cytokines release from human eosinophils

BACKGROUND: Subepithelial fibrosis is one of the most critical structural changes affecting bronchial airway function during asthma. Eosinophils have been shown to contribute to the production of pro-fibrotic cytokines, TGF-β and IL-11, however, the mechanism regulating this process is not fully und...

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Detalles Bibliográficos
Autores principales: Al-Muhsen, Saleh, Letuve, Severine, Vazquez-Tello, Alejandro, Pureza, Mary Angeline, Al-Jahdali, Hamdan, Bahammam, Ahmed S, Hamid, Qutayba, Halwani, Rabih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602055/
https://www.ncbi.nlm.nih.gov/pubmed/23496774
http://dx.doi.org/10.1186/1465-9921-14-34