Cargando…
p53 Gene Targeting by Homologous Recombination in Fish ES Cells
BACKGROUND: Gene targeting (GT) provides a powerful tool for the generation of precise genetic alterations in embryonic stem (ES) cells to elucidate gene function and create animal models for human diseases. This technology has, however, been limited to mouse and rat. We have previously established...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602087/ https://www.ncbi.nlm.nih.gov/pubmed/23527183 http://dx.doi.org/10.1371/journal.pone.0059400 |