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p53 Gene Targeting by Homologous Recombination in Fish ES Cells

BACKGROUND: Gene targeting (GT) provides a powerful tool for the generation of precise genetic alterations in embryonic stem (ES) cells to elucidate gene function and create animal models for human diseases. This technology has, however, been limited to mouse and rat. We have previously established...

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Detalles Bibliográficos
Autores principales:	Yan, Yan, Hong, Ni, Chen, Tiansheng, Li, Mingyou, Wang, Tiansu, Guan, Guijun, Qiao, Yongkang, Chen, Songlin, Schartl, Manfred, Li, Chang-Ming, Hong, Yunhan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602087/ https://www.ncbi.nlm.nih.gov/pubmed/23527183 http://dx.doi.org/10.1371/journal.pone.0059400

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