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Regulation of germ layer formation by pluripotency factors during embryogenesis
The classical pluripotency factors Oct4, Klf4, Sox2, and Nanog are required for the maintenance of pluripotency and self-renewal of embryonic stem (ES) cells and can reprogram terminally differentiated cells into a pluripotent state. Alteration in the levels of these factors in ES cells will cause d...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602094/ https://www.ncbi.nlm.nih.gov/pubmed/23497659 http://dx.doi.org/10.1186/2045-3701-3-15 |