Rhesus Macaque Lymph Node PD-1(hi)CD4(+) T Cells Express High Levels of CXCR5 and IL-21 and Display a CCR7(lo)ICOS(+)Bcl6(+) T-Follicular Helper (Tfh) Cell Phenotype

CD4 T follicular helper (Tfh) cells play a unique and essential role in the generation of B cell responses in the lymph node microenvironment. Here we sought to determine if differential expression of PD-1 could be used to delineate Tfh cells in rhesus macaque lymph nodes (LN). CD3(+)CD4(+) T cells...

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Detalles Bibliográficos
Autores principales: Onabajo, Olusegun O., George, Jeffy, Lewis, Mark G., Mattapallil, Joseph J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602102/
https://www.ncbi.nlm.nih.gov/pubmed/23527264
http://dx.doi.org/10.1371/journal.pone.0059758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602102/
https://www.ncbi.nlm.nih.gov/pubmed/23527264
http://dx.doi.org/10.1371/journal.pone.0059758

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