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Bioenergetic study of murine hepatic tissue treated in vitro with atorvastatin

Atorvastatin (a 3-hydroxy-3-methylglutaryl coenzyme-A reductase inhibitor) is a widely used cholesterol-lowering drug, which is recognized for its potential hepatotoxicity. This study investigated in vitro effects of this agent on hepatic tissue respiration, ATP content, caspase activity, urea synth...

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Detalles Bibliográficos
Autores principales: Alfazari, Ali S, Al-Dabbagh, Bayan, Almarzooqi, Saeeda, Albawardi, Alia, Souid, Abdul-Kader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602108/
https://www.ncbi.nlm.nih.gov/pubmed/23448291
http://dx.doi.org/10.1186/2050-6511-14-15