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Carnosine: can understanding its actions on energy metabolism and protein homeostasis inform its therapeutic potential?

The dipeptide carnosine (β-alanyl-L-histidine) has contrasting but beneficial effects on cellular activity. It delays cellular senescence and rejuvenates cultured senescent mammalian cells. However, it also inhibits the growth of cultured tumour cells. Based on studies in several organisms, we specu...

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Detalles Bibliográficos
Autores principales: Hipkiss, Alan R, Cartwright, Stephanie P, Bromley, Clare, Gross, Stephane R, Bill, Roslyn M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602167/
https://www.ncbi.nlm.nih.gov/pubmed/23442334
http://dx.doi.org/10.1186/1752-153X-7-38