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Carnosine: can understanding its actions on energy metabolism and protein homeostasis inform its therapeutic potential?
The dipeptide carnosine (β-alanyl-L-histidine) has contrasting but beneficial effects on cellular activity. It delays cellular senescence and rejuvenates cultured senescent mammalian cells. However, it also inhibits the growth of cultured tumour cells. Based on studies in several organisms, we specu...
Autores principales: | Hipkiss, Alan R, Cartwright, Stephanie P, Bromley, Clare, Gross, Stephane R, Bill, Roslyn M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602167/ https://www.ncbi.nlm.nih.gov/pubmed/23442334 http://dx.doi.org/10.1186/1752-153X-7-38 |
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