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Novel Interaction between Proliferating Cell Nuclear Antigen and HLA I on the Surface of Tumor Cells Inhibits NK Cell Function through NKp44

NK cell function is closely regulated by numerous inhibitory and activating receptors binding corresponding ligands on the surface of target cells, providing vital first line defenses against infections and cancer. NKp44, originally discovered as an activating NK cell receptor, was recently found to...

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Detalles Bibliográficos
Autores principales: Horton, Nathan C., Mathew, Stephen O., Mathew, Porunelloor A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602199/
https://www.ncbi.nlm.nih.gov/pubmed/23527218
http://dx.doi.org/10.1371/journal.pone.0059552