Fatty Acid Ethyl Esters Induce Intestinal Epithelial Barrier Dysfunction via a Reactive Oxygen Species-Dependent Mechanism in a Three-Dimensional Cell Culture Model

BACKGROUND & AIMS: Evidence is accumulating that ethanol and its oxidative metabolite, acetaldehyde, can disrupt intestinal epithelial integrity, an important factor contributing to ethanol-induced liver injury. However, ethanol can also be metabolized non-oxidatively generating phosphatidyletha...

Descripción completa

Detalles Bibliográficos
Autores principales: Elamin, Elhaseen, Masclee, Ad, Juuti-Uusitalo, Kati, van IJzendoorn, Sven, Troost, Freddy, Pieters, Harm-Jan, Dekker, Jan, Jonkers, Daisy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602318/
https://www.ncbi.nlm.nih.gov/pubmed/23526996
http://dx.doi.org/10.1371/journal.pone.0058561

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602318/
https://www.ncbi.nlm.nih.gov/pubmed/23526996
http://dx.doi.org/10.1371/journal.pone.0058561

Ejemplares similares