Steady-State NTPase Activity of Dengue Virus NS3: Number of Catalytic Sites, Nucleotide Specificity and Activation by ssRNA

Dengue virus nonstructural protein 3 (NS3) unwinds double stranded RNA driven by the free energy derived from the hydrolysis of nucleoside triphosphates. This paper presents the first systematic and quantitative characterization of the steady-state NTPase activity of DENV NS3 and their interaction w...

Descripción completa

Detalles Bibliográficos
Autores principales: Incicco, J. Jeremías, Gebhard, Leopoldo G., González-Lebrero, Rodolfo M., Gamarnik, Andrea V., Kaufman, Sergio B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602377/
https://www.ncbi.nlm.nih.gov/pubmed/23526990
http://dx.doi.org/10.1371/journal.pone.0058508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602377/
https://www.ncbi.nlm.nih.gov/pubmed/23526990
http://dx.doi.org/10.1371/journal.pone.0058508

Ejemplares similares