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Steady-State NTPase Activity of Dengue Virus NS3: Number of Catalytic Sites, Nucleotide Specificity and Activation by ssRNA
Dengue virus nonstructural protein 3 (NS3) unwinds double stranded RNA driven by the free energy derived from the hydrolysis of nucleoside triphosphates. This paper presents the first systematic and quantitative characterization of the steady-state NTPase activity of DENV NS3 and their interaction w...
Autores principales: | Incicco, J. Jeremías, Gebhard, Leopoldo G., González-Lebrero, Rodolfo M., Gamarnik, Andrea V., Kaufman, Sergio B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602377/ https://www.ncbi.nlm.nih.gov/pubmed/23526990 http://dx.doi.org/10.1371/journal.pone.0058508 |
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