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L-Dopa and the Albino Riddle: Content of L-Dopa in the Developing Retina of Pigmented and Albino Mice

BACKGROUND: The absence or deficiency of melanin as in albinos, has detrimental effects on retinal development that include aberrant axonal projections from eye to brain and impaired vision. In pigmented retinal pigment epithelium (RPE), dihydroxyphenalanine (L-Dopa), an intermediate in the syntheti...

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Detalles Bibliográficos
Autores principales: Roffler-Tarlov, Suzanne, Liu, Jin Hong, Naumova, Elena N., Bernal-Ayala, Maria Margarita, Mason, Carol A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602463/
https://www.ncbi.nlm.nih.gov/pubmed/23526936
http://dx.doi.org/10.1371/journal.pone.0057184