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The brain slice method for studying drug distribution in the CNS
The high-throughput brain slice method is a precise and robust technique for estimating the overall uptake of drugs into brain tissue through determination of the unbound volume of distribution in the brain (V(u,brain); ml·g brain(-1)). V(u,brain) describes the relationship between the total drug co...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602653/ https://www.ncbi.nlm.nih.gov/pubmed/23336814 http://dx.doi.org/10.1186/2045-8118-10-6 |