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The brain slice method for studying drug distribution in the CNS

The high-throughput brain slice method is a precise and robust technique for estimating the overall uptake of drugs into brain tissue through determination of the unbound volume of distribution in the brain (V(u,brain); ml·g brain(-1)). V(u,brain) describes the relationship between the total drug co...

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Detalles Bibliográficos
Autores principales:	Loryan, Irena, Fridén, Markus, Hammarlund-Udenaes, Margareta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602653/ https://www.ncbi.nlm.nih.gov/pubmed/23336814 http://dx.doi.org/10.1186/2045-8118-10-6

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