Evidence for the Possible Biological Significance of the igf-1 Gene Alternative Splicing in Prostate Cancer

Insulin-like growth factor-I (IGF-I) has been implicated in the pathogenesis of prostate cancer (PCa), since it plays a key role in cell proliferation, differentiation, and apoptosis. The IGF-I actions are mediated mainly via its binding to the type I IGF receptor (IGF-IR), however IGF-I signaling v...

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Detalles Bibliográficos
Autores principales: Philippou, Anastassios, Armakolas, Athanasios, Koutsilieris, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602724/
https://www.ncbi.nlm.nih.gov/pubmed/23519101
http://dx.doi.org/10.3389/fendo.2013.00031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602724/
https://www.ncbi.nlm.nih.gov/pubmed/23519101
http://dx.doi.org/10.3389/fendo.2013.00031

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