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Low dose bisphenol A impairs spermatogenesis by suppressing reproductive hormone production and promoting germ cell apoptosis in adult rats

Bisphenol A (BPA), an estrogenic chemical, has been shown to reduce sperm count; however, the underlying mechanisms remain unknown. Herein, we show that oral administration of BPA (2 µg/kg) for consecutive 14 days in adult rats (BPA rats) significantly reduced the sperm count and the number of germ...

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Detalles Bibliográficos
Autores principales: Jin, Pengpeng, Wang, Xiaoli, Chang, Fei, Bai, Yinyang, Li, Yingchun, Zhou, Rong, Chen, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Editorial Department of Journal of Biomedical Research 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602871/
https://www.ncbi.nlm.nih.gov/pubmed/23554804
http://dx.doi.org/10.7555/JBR.27.20120076