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Predicted binding of certain antifilarial compounds with glutathione-S-transferase of human Filariids

Glutathione-S-transferase is a major phase-II detoxification enzyme in parasitic helminthes. Previous research highlights the importance of GSTs in the establishment of chronic infections in cytotoxic microenvironments. Filarial nematodes depend on these detoxification enzymes for their survival in...

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Detalles Bibliográficos
Autores principales: Saeed, Mohd, Baig, Mohd Hassan, Bajpai, Preeti, Srivastava, Ashwini Kumar, Ahmad, Khurshid, Mustafa, Huma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602877/
https://www.ncbi.nlm.nih.gov/pubmed/23516334
http://dx.doi.org/10.6026/97320630009233