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Development of Two Distinct Dendritic-Like APCs in the Context of Splenic Stroma
Murine splenic stroma has been found to provide an in vitro niche for hematopoiesis of dendritic-like APC. Two distinct cell types have been characterized. The novel “L-DC” subset has cross-presenting capacity, leading to activation of CD8(+) T cells, but not activating CD4(+) T cells, which is cons...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602895/ https://www.ncbi.nlm.nih.gov/pubmed/23519558 http://dx.doi.org/10.3389/fimmu.2013.00073 |