Enhanced Cytotoxic Effects of Combined Valproic Acid and the Aurora Kinase Inhibitor VE465 on Gynecologic Cancer Cells

Increasing evidence shows that targeting epigenetic changes including acetylation and deacetylation of core nucleosomal histones as well as Aurora kinases hold promise for improving the treatment of human cancers including ovarian cancer. We investigated whether the histone deacetylase (HDAC) inhibi...

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Detalles Bibliográficos
Autores principales: Li, Yanfang, Liu, Tao, Ivan, Cristina, Huang, Jie, Shen, De-Yu, Kavanagh, John J., Bast, Robert C., Fu, Siqing, Hu, Wei, Sood, Anil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602963/
https://www.ncbi.nlm.nih.gov/pubmed/23519775
http://dx.doi.org/10.3389/fonc.2013.00058

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3602963/
https://www.ncbi.nlm.nih.gov/pubmed/23519775
http://dx.doi.org/10.3389/fonc.2013.00058

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