Effect of PSI‐697, a Novel P‐Selectin Inhibitor, on Platelet–Monocyte Aggregate Formation in Humans

BACKGROUND: Platelet activation is central to the pathogenesis of acute coronary syndromes. Surface expression of P‐selectin on activated platelets induces formation of platelet–monocyte aggregates and promotes vascular inflammation and thrombosis. P‐selectin antagonism may represent a novel therape...

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Detalles Bibliográficos
Autores principales: Japp, Alan G., Chelliah, Raj, Tattersall, Laura, Lang, Ninian N., Meng, Xu, Weisel, Kathleen, Katz, Arie, Burt, David, Fox, Keith A. A., Feuerstein, Giora Z., Connolly, Thomas M., Newby, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603266/
https://www.ncbi.nlm.nih.gov/pubmed/23525448
http://dx.doi.org/10.1161/JAHA.112.006007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603266/
https://www.ncbi.nlm.nih.gov/pubmed/23525448
http://dx.doi.org/10.1161/JAHA.112.006007

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