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Mitochondrial NDUFS3 regulates the ROS-mediated onset of metabolic switch in transformed cells

Aerobic glycolysis in transformed cells is an unique metabolic phenotype characterized by a hyperactivated glycolytic pathway even in the presence of oxygen. It is not clear if the onset of aerobic glycolysis is regulated by mitochondrial dysfunction and, if so, what the metabolic windows of opportu...

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Detalles Bibliográficos
Autores principales: Suhane, Sonal, Kanzaki, Hirotaka, Arumugaswami, Vaithilingaraja, Murali, Ramachandran, Ramanujan, V. Krishnan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603411/
https://www.ncbi.nlm.nih.gov/pubmed/23519235
http://dx.doi.org/10.1242/bio.20133244