Yeast-based automated high-throughput screens to identify anti-parasitic lead compounds

We have developed a robust, fully automated anti-parasitic drug-screening method that selects compounds specifically targeting parasite enzymes and not their host counterparts, thus allowing the early elimination of compounds with potential side effects. Our yeast system permits multiple parasite ta...

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Detalles Bibliográficos
Autores principales: Bilsland, Elizabeth, Sparkes, Andrew, Williams, Kevin, Moss, Harry J., de Clare, Michaela, Pir, Pınar, Rowland, Jem, Aubrey, Wayne, Pateman, Ron, Young, Mike, Carrington, Mark, King, Ross D., Oliver, Stephen G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2013
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603448/
https://www.ncbi.nlm.nih.gov/pubmed/23446112
http://dx.doi.org/10.1098/rsob.120158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603448/
https://www.ncbi.nlm.nih.gov/pubmed/23446112
http://dx.doi.org/10.1098/rsob.120158

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