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Functions of BCL-X(L) at the Interface between Cell Death and Metabolism
The BCL-2 homolog BCL-X(L), one of the two protein products of BCL2L1, has originally been characterized for its prominent prosurvival functions. Similar to BCL-2, BCL-X(L) binds to its multidomain proapoptotic counterparts BAX and BAK, hence preventing the formation of lethal pores in the mitochond...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603586/ https://www.ncbi.nlm.nih.gov/pubmed/23533418 http://dx.doi.org/10.1155/2013/705294 |