Gene Therapy with HSV1-sr39TK/GCV Exhibits a Stronger Therapeutic Efficacy Than HSV1-TK/GCV in Rat C6 Glioma Cells

Although the combination of herpes simplex virus type 1 (HSV-1) thymidine kinase (TK) with ganciclovir (GCV) has been shown as a promising suicide gene treatment strategy for glioma, the almost immunodepressive dose of GCV required for its adequate in vivo efficacy has hampered its further clinical...

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Detalles Bibliográficos
Autores principales: Li, Lei-qing, Shen, Fang, Xu, Xiao-yan, Zhang, Hong, Yang, Xiao-feng, Liu, Wei-guo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603674/
https://www.ncbi.nlm.nih.gov/pubmed/23533367
http://dx.doi.org/10.1155/2013/951343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603674/
https://www.ncbi.nlm.nih.gov/pubmed/23533367
http://dx.doi.org/10.1155/2013/951343

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