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Increased Production of IL-4 and IL-12p40 from Bronchoalveolar Lavage Cells Are Biomarkers of Mycobacterium tuberculosis in the Sputum

BACKGROUND: Tuberculosis (TB) causes 1.45 million deaths annually world wide, the majority of which occur in the developing world. Active TB disease represents immune failure to control latent infection from airborne spread. Acid-fast bacillus (AFB) seen on sputum smear is a biomarker for contagious...

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Detalles Bibliográficos
Autores principales: Nolan, Anna, Fajardo, Elaine, Huie, Maryann L., Condos, Rany, Pooran, Anil, Dawson, Rodney, Dheda, Keertan, Bateman, Eric, Rom, William N., Weiden, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603887/
https://www.ncbi.nlm.nih.gov/pubmed/23527200
http://dx.doi.org/10.1371/journal.pone.0059461