Toxoplasma gondii Triggers Phosphorylation and Nuclear Translocation of Dendritic Cell STAT1 while Simultaneously Blocking IFNγ-Induced STAT1 Transcriptional Activity

The protozoan Toxoplasma gondii actively modulates cytokine-induced JAK/STAT signaling pathways to facilitate survival within the host, including blocking IFNγ-mediated STAT1-dependent proinflammatory gene expression. We sought to further characterize inhibition of STAT1 signaling in infected murine...

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Detalles Bibliográficos
Autores principales: Schneider, Anne G., Abi Abdallah, Delbert S., Butcher, Barbara A., Denkers, Eric Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603897/
https://www.ncbi.nlm.nih.gov/pubmed/23527309
http://dx.doi.org/10.1371/journal.pone.0060215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603897/
https://www.ncbi.nlm.nih.gov/pubmed/23527309
http://dx.doi.org/10.1371/journal.pone.0060215

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