Pioglitazone Improves Cognitive Function via Increasing Insulin Sensitivity and Strengthening Antioxidant Defense System in Fructose-Drinking Insulin Resistance Rats

Insulin resistance (IR) links Alzheimer’s disease (AD) with oxidative damage, cholinergic deficit, and cognitive impairment. Peroxisome proliferator-activated receptor γ (PPARγ) agonist pioglitazone previously used to treat type 2 diabetes mellitus (T2DM) has also been demonstrated to be effective i...

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Detalles Bibliográficos
Autores principales: Yin, Qing-Qing, Pei, Jin-Jing, Xu, Song, Luo, Ding-Zhen, Dong, Si-Qing, Sun, Meng-Han, You, Li, Sun, Zhi-Jian, Liu, Xue-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603906/
https://www.ncbi.nlm.nih.gov/pubmed/23527159
http://dx.doi.org/10.1371/journal.pone.0059313

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603906/
https://www.ncbi.nlm.nih.gov/pubmed/23527159
http://dx.doi.org/10.1371/journal.pone.0059313

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