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Functionalized Graphene Oxide Mediated Adriamycin Delivery and miR-21 Gene Silencing to Overcome Tumor Multidrug Resistance In Vitro

Multidrug resistance (MDR) is a major impediment to successful cancer chemotherapy. Co-delivery of novel MDR-reversing agents and anticancer drugs to cancer cells holds great promise for cancer treatment. MicroRNA-21 (miR-21) overexpression is associated with the development and progression of MDR i...

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Detalles Bibliográficos
Autores principales: Zhi, Feng, Dong, Haifeng, Jia, Xuefeng, Guo, Wenjie, Lu, Huiting, Yang, Yilin, Ju, Huangxian, Zhang, Xueji, Hu, Yiqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603917/
https://www.ncbi.nlm.nih.gov/pubmed/23527297
http://dx.doi.org/10.1371/journal.pone.0060034