Alternative Processing of the U2 Small Nuclear RNA Produces a 19–22nt Fragment with Relevance for the Detection of Non-Small Cell Lung Cancer in Human Serum

RNU2 exists in two functional forms (RNU2-1 and RNU2-2) distinguishable by the presence of a unique 4-bases motif. Detailed investigation of datasets obtained from deep sequencing of five human lung primary tumors revealed that both forms express at a high rate a 19–22nt fragment (miR-U2-1 and -2) f...

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Detalles Bibliográficos
Autores principales: Mazières, Julien, Catherinne, Caroline, Delfour, Olivier, Gouin, Sandrine, Rouquette, Isabelle, Delisle, Marie-Bernadette, Prévot, Grégoire, Escamilla, Roger, Didier, Alain, Persing, David H., Bates, Mike, Michot, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603938/
https://www.ncbi.nlm.nih.gov/pubmed/23527303
http://dx.doi.org/10.1371/journal.pone.0060134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603938/
https://www.ncbi.nlm.nih.gov/pubmed/23527303
http://dx.doi.org/10.1371/journal.pone.0060134

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