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Mitochondrial DAMPs Increase Endothelial Permeability through Neutrophil Dependent and Independent Pathways

Trauma and sepsis can cause acute lung injury (ALI) and Acute Respiratory Distress Syndrome (ARDS) in part by triggering neutrophil (PMN)-mediated increases in endothelial cell (EC) permeability. We had shown that mitochondrial (mt) damage-associated molecular patterns (DAMPs) appear in the blood af...

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Detalles Bibliográficos
Autores principales: Sun, Shiqin, Sursal, Tolga, Adibnia, Yasaman, Zhao, Cong, Zheng, Yi, Li, Haipeng, Otterbein, Leo E., Hauser, Carl J., Itagaki, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603956/
https://www.ncbi.nlm.nih.gov/pubmed/23527291
http://dx.doi.org/10.1371/journal.pone.0059989