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Inhibition of Histone Deacetylase Impacts Cancer Stem Cells and Induces Epithelial-Mesenchyme Transition of Head and Neck Cancer
The genome is organized and packed into the nucleus through interactions with core histone proteins. Emerging evidence suggests that tumors are highly responsive to epigenetic alterations that induce chromatin-based events and dynamically influence tumor behavior. We examined chromatin organization...
Autores principales: | Giudice, Fernanda S., Pinto, Decio S., Nör, Jacques E., Squarize, Cristiane H., Castilho, Rogerio M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603970/ https://www.ncbi.nlm.nih.gov/pubmed/23527004 http://dx.doi.org/10.1371/journal.pone.0058672 |
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