Rescue of MHC-1 Antigen Processing Machinery by Down-Regulation in Expression of IGF-1 in Human Glioblastoma Cells

Escape from immune recognition has been hypothesized to be a factor in carcinogenesis. It may be mediated for many cancers through down-regulation in the MHC class 1 antigen processing and presentation pathway. TAP-1, TAP-2, tightly linked to LMP-2 and LMP-7 are multiple components of the endogenous...

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Detalles Bibliográficos
Autores principales: Pan, Yuexin, Trojan, Jerzy, Guo, Yajun, Anthony, Donald D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603982/
https://www.ncbi.nlm.nih.gov/pubmed/23526983
http://dx.doi.org/10.1371/journal.pone.0058428

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603982/
https://www.ncbi.nlm.nih.gov/pubmed/23526983
http://dx.doi.org/10.1371/journal.pone.0058428

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