Pharmacological Inhibition of Glycogen Synthase Kinase 3 Regulates T Cell Development In Vitro

The development of functional T cells requires receptor-mediated transition through multiple checkpoints in the thymus. Double negative 3 (DN3) thymocytes are selected for the presence of a rearranged TCR beta chain in a process termed β-selection which requires signalling via the pre-TCR, Notch1 an...

Descripción completa

Detalles Bibliográficos
Autores principales: Schroeder, Jan-Hendrik, Bell, Lewis S., Janas, Michelle L., Turner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603984/
https://www.ncbi.nlm.nih.gov/pubmed/23526989
http://dx.doi.org/10.1371/journal.pone.0058501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603984/
https://www.ncbi.nlm.nih.gov/pubmed/23526989
http://dx.doi.org/10.1371/journal.pone.0058501

Ejemplares similares