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Fine Mapping for Weaver Syndrome in Brown Swiss Cattle and the Identification of 41 Concordant Mutations across NRCAM, PNPLA8 and CTTNBP2

Bovine Progressive Degenerative Myeloencephalopathy (Weaver Syndrome) is a recessive neurological disease that has been observed in the Brown Swiss cattle breed since the 1970’s in North America and Europe. Bilateral hind leg weakness and ataxia appear in afflicted animals at 6 to 18 months of age,...

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Detalles Bibliográficos
Autores principales: McClure, Matthew, Kim, Euisoo, Bickhart, Derek, Null, Daniel, Cooper, Tabatha, Cole, John, Wiggans, George, Ajmone-Marsan, Paolo, Colli, Licia, Santus, Enrico, Liu, George E., Schroeder, Steve, Matukumalli, Lakshmi, Van Tassell, Curt, Sonstegard, Tad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3603989/
https://www.ncbi.nlm.nih.gov/pubmed/23527149
http://dx.doi.org/10.1371/journal.pone.0059251