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Chemerin Is an Antimicrobial Agent in Human Epidermis

Chemerin, a chemoattractant ligand for chemokine-like receptor 1 (CMKLR1) is predicted to share similar tertiary structure with antibacterial cathelicidins. Recombinant chemerin has antimicrobial activity. Here we show that endogenous chemerin is abundant in human epidermis, and that inhibition of b...

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Detalles Bibliográficos
Autores principales: Banas, Magdalena, Zabieglo, Katarzyna, Kasetty, Gopinath, Kapinska-Mrowiecka, Monika, Borowczyk, Julia, Drukala, Justyna, Murzyn, Krzysztof, Zabel, Brian A., Butcher, Eugene C., Schroeder, Jens M., Schmidtchen, Artur, Cichy, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604073/
https://www.ncbi.nlm.nih.gov/pubmed/23527010
http://dx.doi.org/10.1371/journal.pone.0058709