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Transcriptome Sequencing of Tumor Subpopulations Reveals a Spectrum of Therapeutic Options for Squamous Cell Lung Cancer

BACKGROUND: The only therapeutic options that exist for squamous cell lung carcinoma (SCC) are standard radiation and cytotoxic chemotherapy. Cancer stem cells (CSCs) are hypothesized to account for therapeutic resistance, suggesting that CSCs must be specifically targeted. Here, we analyze the tran...

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Detalles Bibliográficos
Autores principales: Barrett, Christian L., Schwab, Richard B., Jung, HyunChul, Crain, Brian, Goff, Daniel J., Jamieson, Catriona H. M., Thistlethwaite, Patricia A., Harismendy, Olivier, Carson, Dennis A., Frazer, Kelly A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604164/
https://www.ncbi.nlm.nih.gov/pubmed/23527012
http://dx.doi.org/10.1371/journal.pone.0058714