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Transcriptome Sequencing of Tumor Subpopulations Reveals a Spectrum of Therapeutic Options for Squamous Cell Lung Cancer
BACKGROUND: The only therapeutic options that exist for squamous cell lung carcinoma (SCC) are standard radiation and cytotoxic chemotherapy. Cancer stem cells (CSCs) are hypothesized to account for therapeutic resistance, suggesting that CSCs must be specifically targeted. Here, we analyze the tran...
Autores principales: | Barrett, Christian L., Schwab, Richard B., Jung, HyunChul, Crain, Brian, Goff, Daniel J., Jamieson, Catriona H. M., Thistlethwaite, Patricia A., Harismendy, Olivier, Carson, Dennis A., Frazer, Kelly A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604164/ https://www.ncbi.nlm.nih.gov/pubmed/23527012 http://dx.doi.org/10.1371/journal.pone.0058714 |
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