Comparison of the transport of QX-314 through TRPA1, TRPM8, and TRPV1 channels

BACKGROUND: It has been demonstrated that N-ethyl-lidocaine (QX-314) can target the transient receptor protein vanilloid 1 (TRPV1) nociceptors when coadministered with capsaicin, resulting in a selective block of the nociceptors. Capsaicin is problematic in therapeutic use because it induces firing...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakagawa, Hiroshi, Hiura, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604974/
https://www.ncbi.nlm.nih.gov/pubmed/23525210
http://dx.doi.org/10.2147/JPR.S41614

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3604974/
https://www.ncbi.nlm.nih.gov/pubmed/23525210
http://dx.doi.org/10.2147/JPR.S41614

Ejemplares similares