Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development

Yap is a transcriptional co-activator that regulates cell proliferation and apoptosis downstream of the Hippo kinase pathway. We investigated Yap function during mouse kidney development using a conditional knockout strategy that specifically inactivated Yap within the nephrogenic lineage. We found...

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Detalles Bibliográficos
Autores principales: Reginensi, Antoine, Scott, Rizaldy P., Gregorieff, Alex, Bagherie-Lachidan, Mazdak, Chung, Chaeuk, Lim, Dae-Sik, Pawson, Tony, Wrana, Jeff, McNeill, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605093/
https://www.ncbi.nlm.nih.gov/pubmed/23555292
http://dx.doi.org/10.1371/journal.pgen.1003380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605093/
https://www.ncbi.nlm.nih.gov/pubmed/23555292
http://dx.doi.org/10.1371/journal.pgen.1003380

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