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Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development
Yap is a transcriptional co-activator that regulates cell proliferation and apoptosis downstream of the Hippo kinase pathway. We investigated Yap function during mouse kidney development using a conditional knockout strategy that specifically inactivated Yap within the nephrogenic lineage. We found...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605093/ https://www.ncbi.nlm.nih.gov/pubmed/23555292 http://dx.doi.org/10.1371/journal.pgen.1003380 |