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Inferring Metabolic States in Uncharacterized Environments Using Gene-Expression Measurements

The large size of metabolic networks entails an overwhelming multiplicity in the possible steady-state flux distributions that are compatible with stoichiometric constraints. This space of possibilities is largest in the frequent situation where the nutrients available to the cells are unknown. Thes...

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Detalles Bibliográficos
Autores principales: Rossell, Sergio, Huynen, Martijn A., Notebaart, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605102/
https://www.ncbi.nlm.nih.gov/pubmed/23555222
http://dx.doi.org/10.1371/journal.pcbi.1002988