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Analysis of Physicochemical and Structural Properties Determining HIV-1 Coreceptor Usage
The relationship of HIV tropism with disease progression and the recent development of CCR5-blocking drugs underscore the importance of monitoring virus coreceptor usage. As an alternative to costly phenotypic assays, computational methods aim at predicting virus tropism based on the sequence and st...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605109/ https://www.ncbi.nlm.nih.gov/pubmed/23555214 http://dx.doi.org/10.1371/journal.pcbi.1002977 |