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Analysis of Physicochemical and Structural Properties Determining HIV-1 Coreceptor Usage

The relationship of HIV tropism with disease progression and the recent development of CCR5-blocking drugs underscore the importance of monitoring virus coreceptor usage. As an alternative to costly phenotypic assays, computational methods aim at predicting virus tropism based on the sequence and st...

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Detalles Bibliográficos
Autores principales:	Bozek, Katarzyna, Lengauer, Thomas, Sierra, Saleta, Kaiser, Rolf, Domingues, Francisco S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3605109/ https://www.ncbi.nlm.nih.gov/pubmed/23555214 http://dx.doi.org/10.1371/journal.pcbi.1002977

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